Lafayette Street is a major north-south street in New York City's Lower Manhattan. It originates at the intersection of Reade Street and Centre Street, one block north of Chambers Street. The one-way street then successively runs through Chinatown, Little Italy, NoLIta, and NoHo and finally, between East 9th and East 10th Streets, merges with Fourth Avenue. A buffered bike lane runs outside the left traffic lane. Houston Street is a major east-west thoroughfare in downtown Manhattan, running crosstown across the full width of the island of Manhattan, from Franklin D. Roosevelt East River Drive and East River Park on the East River to Pier 40 and West Street on the Hudson River.